The effectiveness of the lidocaine was studied in a split-face clinical study of 60 patients. Each patient received Restylane® Lyft without Lidocaine on one side of the face and Restylane® Lyft with Lidocaine on the other side of the face for the treatment of lines around the nose and mouth. Restylane® Lyft with Lidocaine significantly reduced the pain of the injection.
For the side of the face treated with Restylane® Lyft without Lidocaine, patients rated their pain as about 47 on a scale of 0 to 100 after injection.
For the side of the face treated with Restylane® Lyft with Lidocaine, patients rated their pain as about 15 on the same scale.
Pain relief from the lidocaine in Restylane® Lyft with Lidocaine lasted up to 60 minutes after treatment.